Distribution of antiseptic resistance genes qacA, qacB, and smr in methicillin-resistant Staphylococcus aureus isolated in Toronto, Canada, from 2005 to 2009.

نویسندگان

  • Jean Longtin
  • Christine Seah
  • Krystal Siebert
  • Allison McGeer
  • Andrew Simor
  • Yves Longtin
  • Donald E Low
  • Roberto G Melano
چکیده

Decreased susceptibility to chlorhexidine gluconate (CHDN) in methicillin-resistant Staphylococcus aureus (MRSA) is associated with the qacA, qacB, and smr genes, encoding efflux pumps. A total of 334 MRSA isolates were collected from two Canadian intensive care units between 2005 and 2009. We identified the qacAB genes in 7 strains (2%; 2 qacA genes and 5 qacB genes) and the smr gene in 23 (7%) strains. CHDN minimal bactericidal concentrations were slightly higher for strains harboring smr genes.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 55 6  شماره 

صفحات  -

تاریخ انتشار 2011